It has come about because farmers the world over have been routinely administering antibiotics to their animals. Add that to doctors prescribing antibiotics to patients who do not need them and the antibiotic apocalypse looms.
The following quote is particularly pertinent to me as I was treated there for a blood infection last December. I was on drips of two antibiotics and only once they began to kick in was I allowed home on the same antibiotics taken orally.
"The transfer rate of this resistance gene is ridiculously high, that doesn't look good," said Prof Mark Wilcox, from Leeds Teaching Hospitals NHS Trust.
His hospital is now dealing with multiple cases "where we're struggling to find an antibiotic" every month - an event he describes as being as "rare as hens' teeth" five years ago.
He said there was no single event that would mark the start of the antibiotic apocalypse, but it was clear "we're losing the battle".